Глазная артерия velocimetry в преэклампсии. Острый живот как необычное проявление тяжелой преэклампсии, страница 9

TI: Pathological studies on the placenta from pre-term and term maternal toxicosis.

TI: Патологическое исследование плаценты от пред-срока(термина) и называет материнский токсикоз.

AU: Nishimura-Y; Hanioka-K; Itoh-H; Kubota-A

AD: Department of Pathology, Kobe University School of Medicine.

SO: Kobe-J-Med-Sci. 1994 Feb; 40(1): 13-24

AB: Fifty one placentae with maternal pre-term and term toxicosis were studied pathologically. In the severe pre-term maternal toxicosis, the placenta reveals hyperplasia of syncytial cytotrophoblasts(S-cells) with knots, fibrin deposit at their surface, fibrinoid degeneration of the stroma, in addition to marked interstitial fibrosis of chorionic villi. The basement membrane is thick and cytotrophoblasts(C-cells) are scattered beneath it. Decidual arteries are hyalinized, but a few decidual arteries are thick and almost obstructed in their lumina. On the other hand, the placenta of maternal term toxicosis show chorionic villi with few C-cells under the thin S-cell lining. Their basement membrane is thin with well developed vasculosyncytial membrane. Decidual arteries are more hyalinized and widened. These pathological changes seen in term maternal toxicosis are the severer than those of placental aging.

: Пятьдесят один placentae с материнским пред-сроком(термином) и токсикозом срока(термина) были изучены патологически. В тяжелом пред-сроке(термине) материнский токсикоз, плацента показывает гиперплазию syncytial cytotrophoblasts (s - Ячейки) с узлами, осадок фибрина в их поверхности, дегенерация фибриноида стромы, в дополнение к отмеченному внутритканевому фиброзу хориального villi. Подвальная мембрана толста и cytotrophoblasts (c - Ячейки) рассеяны ниже этого. decidual артерии - hyalinized, но несколько decidual артерии толст и почти затруднен в их lumina. С другой стороны, плацента материнского токсикоза срока(термина) показывает хориальный villi с немногими C - Ячейки под тонким S - покров Ячейки. Их подвальная мембрана тонка с хорошо развитой vasculosyncytial мембраной. decidual артерии - большее количество hyalinized и расширенный. Эти патологические изменения(замены), замеченные в сроке(термине) материнский токсикоз более тяжелы чем таковые плацентарного старения.

TI: The value of antithrombin-III and fibronectin in hypertensive disorders of pregnancy.

TI: ценность antithrombin-III и фибронектина в гипертензивных нарушениях беременности.

AU: Sen-C; Madazh-R; Kavuzlu-C; Ocak-V; Tolun-N

AD: Department of Perinatology, Obstetrics and Gynaecology, Cerrahpasa Medical School, University of Istanbul, Turkey.

SO: J-Perinat-Med. 1994; 22(1): 29-38

AB: In this study we evaluated fibronectin as a marker of endothelial cell injury and antithrombin III as a marker of chronic activation of intravascular coagulation. The aim of the study was to establish to normal trends of plasma antithrombin III and fibronectin in general obstetric population and to determine the value of both in predicting, distinguishing and understanding the pathophysiology of pregnancy induced hypertension. The all cases consisted of 173 pregnant, 19 of them were chronic hypertensive, 45 were pregnancy induced hypertensive and 119 were normotensive at blood sampling. Out of 119 normotensive cases, 109 cases had no adverse outcome during their pregnancy. These cases were used as a control group and for the normal trends of antithrombin III and fibronectin in general obstetric population. Ten out of 119 cases who developed preeclampsia during follow up, 19 cases with chronic hypertension and 45 cases with pregnancy induced hypertension consisted of the study group. In the cases who developed preeclampsia during follow up, the value of plasma fibronectin level (above 95% confidence limit for that gestational week) to predict preeclampsia had 90% sensitivity and 94.4% specificity. In distinguishing hypertensive disorders of pregnancy (chronic hypertension or pregnancy induced hypertension) fibronectin had 71.1% sensitivity and 100% specificity. Plasma antithrombin III level (of antigenicity) measured by immunodiffusion method had no value in predicting and distinguishing pregnancy induced hypertension.